Targeted radiation therapy can be effective in reducing the size of a tumor, but it can leave bones more susceptible to fractures in the years after cancer.
Studying stem cells for possible solutions are Megan Oest, PhD, assistant professor of orthopedic surgery, and Timothy Damron, MD, professor of orthopedic surgery, cell and developmental biology and neuroscience and physiology. Stem cells have the ability to develop into many different cell types, depending on the body’s needs.
Of the bone cells that are alive at the time of radiation, Oest and Damron have noticed that some die and are never replenished. They are experimenting with chemical or biological methods to prevent damage to these particular cells. Perhaps in the future, patients could receive an injection of a protective substance before undergoing radiotherapy.
It’s also possible, Oest theorizes, that patients could undergo something like a stem cell transplant after their therapy. Healthy cells could come from a donor, or from elsewhere in the patient’s body. She and Damron have learned that when radiation is applied to one leg, cells from the opposite leg remain undamaged. “In theory, if it worked, you could actually take cells from the healthy side of the patient and put them into the unhealthy side,” she says.
Oest and Damron are among dozens of researchers who have received grants from the Carol M. Baldwin Breast Cancer Research Fund of CNYsince 2002.
Megan Oest, PhD: Radiotherapy-associated bone damage[ 0.01 MB ]Play Now | Download
Obstetrician/gynocologist Alexandra Spadola, MD, medical director of the Regional Perinatal Center, provides an overview of the comprehensive services available to women with special needs during pregnancy. The center’s mission is to provide high-quality, compassionate care to patients with complicated pregnancies throughout the Central New York Region, using a multi-disciplinary team approach utilizing physicians, nurses and other health care professionals in an integrated service.
Alexandra Spadola, MD: Comprehensive care for patients with complicated pregnancies[ 0.01 MB ]Play Now | Download
Juliann Mellen, RD, Upstate registered dietitian and certified diabetic educator, reinforces the importance of eating healthy during pregnancy, but cautions that not all foods are safe, and foodborne illness is a serious issue. Read more: FoodSafety.gov
Juliann Mellen, Upstate registered dietitian and certified diabetic educator, reminds us that maintaining healthy eating habits along with regular physical activity during pregnancy is one of the best things you can do for yourself and your baby. MyPlate.gov
Juliann Mellen, RD: Eating healthy during pregnancy[ 0.01 MB ]Play Now | Download
Upstate’s Jayne Charlamb, MD, medical director of prevention and survivorship, talks about a new breast cancer survivorship program for women who have completed their active treatment (chemo, radiation, surgery). The program focuses on empowering and educating participants to take an active role in decisions related to their follow-up care, wellness and comprehensive healthy living. Support Services at Upstate. For more information, call (315) 464-8224.
Jayne R Charlamb, MD, FACP, IBCLC: Upstate's new breast cancer survivorship program[ 0.01 MB ]Play Now | Download
Jayne Charlamb, MD, medical director of prevention and survivorship at Upstate, talks about a program designed for women who are at an increased risk of breast cancer. Charlamb is the director of Upstate’s breast cancer high risk program, which offers special surveillance options as well as “chemoprevention” – taking medication to reduce their risk of developing breast cancer. For more information, call (315) 464-8224, ask for Linda.
Jayne R Charlamb, MD, FACP, IBCLC: Breast cancer high risk program at Upstate[ 0.01 MB ]Play Now | Download
Onondaga County Health Commissioner Cynthia Morrow, MD, MPH is joined by Gail Banach, director of Public Education & Communications for the Upstate New York Poison Center, to talk about local efforts to reduce the number of babies born to drug-dependent moms in Onondaga County. For free and confidential support call the Hopeline at (315) 218-1965.
Cynthia Morrow, MD, MPH and Gail Banach, MS, MSEd, BA: Local efforts to reduce number of babies born to drug-dependent moms[ 0.01 MB ]Play Now | Download