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Archive for the ‘ research-biomedical/clinical’ Category

Aging can bring both negative and positive attitudes, SU researcher finds

Monday, July 6th, 2015

Merril Silverstein, Ph.DMerril Silverstein, PhD, a professor of sociology and social work at Syracuse University, describes the decline in people’s “sense of coherence,” or how to find life meaningful and manageable, as they age. His research showed a predictable decline after midlife, but he also found a surprising result that suggests the positive effect of wisdom.


How the artificial pancreas could improve the lives of people with diabetes

Wednesday, March 11th, 2015

Ruth S Weinstock, MD, PhDPeople with Type 1 diabetes would not have to check their blood sugar levels 12 times a day or worry about wild fluctuations while they slept if an experimental bionic pancreas works as designed, according to Ruth Weinstock, MD, medical director of Upstate’s Joslin Diabetes Center. She describes how the pancreas works in this interview. “It’s not a cure, but it’s definitely a step forward.” For details on participating in research at Joslin, please call 315-464-9007.


Treatment trials may lead to modification of muscular dystrophy diseases

Wednesday, March 11th, 2015

Deborah Y Bradshaw, MDNeurologist Deborah Bradshaw, MD, shares her excitement about two types of disease-modifying treatments that are in clinical trial and could have a profound effect on people who have muscular dystrophy.

“Because we know finally what’s wrong in the gene, how that translates to an abnormal protein and how the protein may be processed abnormally in the cell, we’re actually designing drugs that interrupt that pathway and may, literally, change the course of a genetic disease,” said Bradshaw. “It is amazing.”


Upstate seeks participants for national Alzheimer’s study

Wednesday, March 11th, 2015

Amy E Sanders, MD, MSResearchers at Upstate are seeking patients with mild to moderate Alzheimer’s diseases for a national study of a promising new medication. “It may have the potential to modify the pace of the disease,” neurologist Amy Sanders, MD, said of the drug, called T-817MA. Participants must be between the ages of 55 and 85 with a diagnosis of Alzheimer’s disease and currently taking donepezil, or Aricept. Also in this interview, Sanders discusses what to expect as a normal part of cognitive aging.


Would you volunteer for a dengue fever study?

Thursday, February 26th, 2015

Mark E Polhemus, MDMark Polhemus, MD, tells what volunteers can expect if they participate in a trial designed to help find a vaccine for dengue fever. The study will take place in Syracuse, lasting about 20 months and requiring 23 or 24 medical visits. Adults from 18 to 45 are invited to participate. Learn more at http://www.upstate.edu/cghats/.


Why running is better than walking

Thursday, January 8th, 2015

Carol Sames, PhDPeople who walk regularly for exercise may notice that their speed declines and they tire more easily as they age.

But is that because they are aging? Could that reduction in walking economy be slowed or reversed by other types of exercise, such as running?

Upstate Medical University exercise physiologist Carol Sames explains how running was found to be more beneficial than walking in an intriguing study that compared walkers and runners in Boulder, Colorado. She says running is not appropriate for everyone, and she offers some other ways walkers can add intensity to their workouts.


Proper treatment of nosebleeds

Thursday, December 18th, 2014

Jennifer Villwock, MDEarly intervention within the first 24 hours of a severe nosebleed can improve the outcomes, according to research by Jennifer Villwock, MD, a fourth-year resident in otolaryngology at Upstate Medical University. She studied more than 59,000 cases involving the treatment of epistaxis, the medical word for nosebleeds. In this interview, she talks about what causes nosebleeds and how best to treat them.


New vision research leader expects to see more collaborative science projects

Thursday, December 11th, 2014

William Brunken, PhDScientist William Brunken, PhD, talks about his new role as vice chair for research in Ophthalmology and his research into laminin and laminin-related proteins. Brunken is a professor of ophthalmology and of neurosciene and physiology who will lead a group of vision researchers at Upstate in collaborations with researchers from other SUNY campuses through the SUNY Eye Institute.


Retinal repair research

Friday, November 21st, 2014

Michael Zuber, PhDAndrea Viczian, PhDScientists Andrea Viczian, PhD, and Michael E. Zuber, PhD, are searching for ways to replace cells that are lost during retinal degeneration. Their work centers on finding an efficient method of converting stem cells into retinal cells. It is paid for with a grant designed to stimulate collaboration among researchers at State University of New York campuses.


ADHD research

Thursday, November 13th, 2014

Stephen Faraone, PhDAttention Deficit Hyperactivity Disorder is not the result of modern society. The first evidence of the disorder dates back to the early 19th century, when doctors described signs and symptoms of what we now know as ADHD, says Stephen Faraone, PhD, an Upstate scientist who specializes in ADHD research. In this segment, he discusses possible causes of ADHD, its relation to autism and the likelihood that children could “outgrow” ADHD by the time they reach adulthood.


Upstate pediatric mental health researchers receive $2.8 million federal grant

Wednesday, November 5th, 2014

Stephen Glatt, PhDStephen Glatt, PhD, explains a pediatric mental health project that recently received a $2.8 million federal grant. He and colleagues are looking for 700 families to participate in the project, which explores the genetic similarities among children with a variety of behavioral, emotional or psychiatric disorders. Glatt is the director of the Psychiatric Genetic Epidemiology and Neurobiology Laboratory at Upstate Medical University. 


Putting ‘regeneration’ into regenerative medicine

Wednesday, October 22nd, 2014

Michael Zuber, PhDReyna Martinez-deLuna, PhDMichael Zuber, PhD, and Reyna Martinez-deLuna, PhD, talk of the promising future of research into blinding diseases such as age-related macular degeneration, glaucoma and diabetic retinopathy. They are among the vision researchers working toward regenerating neurons and neural connections in the eye and visual system. They work in the Center for Vision Research in the Department of Opthalmology at Upstate.